The amount of items you can equip is crazy, as usual, for a compo entry :) My only major grief is with the controls: why do you create complicated control schemes when simple solutions would just work (ie. the gun aiming)? :P
Also, many items have super obscure effects and if you skip reading the description (happened accidentally a few times), you cannot guess what effect they have. I would definitely recommend less items and more polish on controls, but that's a very personal approach here ^^
Anyway, I probably died 20-25 times before beating the game but it was still definitely fun :)