Sheep Town by ShredWheat
The gameplay graphics themself are pretty crude, but the GUI is pretty and slick, hence the 4 points.
One point off from gameplay theme for not having destruction.
I was going to rate Gameplay higher at first, but after figuring out how the farmers work and what to build first, there isn't really that much to do. Maybe some events like wolves that make you brake your "sheperds in, sheperds out"-routine would have helped.
Nevertheless, a great display of game design skills for a 48h game.